陈涛简历
陈涛,男,42 岁,医学博士,第四军医大学基础医学院人体解剖与组织胚胎学教研室教授、副主任,博士生导师。国家级精品课、国家级教学团队骨干成员,校精品课教员。获首届全国基础医学青年教师授课比赛二等奖。中国人民解放军原总后勤部科技新星,总后装备部专家库成员,军队特殊人才津贴(二类)。
近年主要从事慢性痛的中枢调控机制的基础研究。专业特长为神经形态学及电生理学研究。至今,共发表SCI 收录论文60篇,总影响因子380,H因子20。其中,以通讯作者和第一作者在 Science , Nature Communications, Neuropsychopharmachology , JNeurosci, Cereb cortex等神经科学和痛觉研究权威学术刊物发表论文20篇,平均影响因子6.8,引用400余次。以共同作者在Nature,Neuron,Brain,Sci Transl Med,JNeurosci等发表多篇论文。在国际学术会议上报告论文6篇,并多次获邀在国际学术会议发言。以项目负责人承担国家自然科学基金项目3项,加拿大国立健康研究院(CIHR)博士后科研基金1项,军队重大项目子课题1项。总资助经费400万。并参加多个国家和军队重大及重点课题。
Featured articles:
lWangJiejie, Lv Xinyou, Wu Yu, Xu Tao, Jiao Mingfei, Chen Ming, Yan Yinggang, ChenChangwan, Dong Weifan, Yang Wei, Zhuo Min, Chen Tao(*), Luo Jianhong*,and Qiu Shuang*. Postsynaptic RIM1modulates synaptic function by facilitating membrane delivery of recyclingNMDARs in hippocampal neurons.Nature Communications 2018 Jun11;9(1):2267.
lChen Tao(#),Taniguchi Wataru, Chen Qi-Yu, Tozaki-Saitoh Hidetoshi, Song Qian,Liu Ren-Hao, Koga Kohei, Matsuda Tsuyoshi, Kaito-Sugimura Yae, Wang Jian, LiZhi-Hua, Lu Ya-Cheng, Inoue Kazuhide, Tsuda Makoto, Li Yun-Qing *, NakatsukaTerumasa *, Zhuo Min *. Top-down descendingfacilitation of spinal sensory excitatory transmission from the anteriorcingulate cortex. Nature Communications 2018,9:1886.
lSongQ, Zheng HW, Li XH, Huganir RL, Kuner T, Zhuo M, Chen T(*). SelectivePhosphorylation of AMPA Receptor Contributes to the Network of Long-TermPotentiation in the Anterior Cingulate Cortex. J Neurosci. 2017 Aug30;37(35):8534-8548.
lLiXH, Song Q, Chen T(*), Zhuo M*. Characterization of postsynaptic calciumsignals in the pyramidal neurons of anterior cingulate cortex. Mol Pain. 2017Jan-Dec;13:1744806917719847.
lZhangK, Li YJ, Guo Y, Zheng KY, Yang Q, Yang L, Wang XS, Song Q, Chen T, ZhuoM, Zhao MG. Elevated progranulin contributes to synaptic and learning deficitdue to loss of fragile X mental retardation protein. Brain. 2017 Dec1;140(12):3215-3232.
lChen,Tao(#), Li, Jing,Feng,Ban,Hui,Rui,Dong,Yu-Lin,Huo,Fu-Quan,Zhang,Ting,Yin,Jun-Bin,Du,Jian-Qing,Li, Yun-Qing(*).Mechanism Underlying the Analgesic Effect Exerted by Endomorphin-1 in the ratVentrolateral Periaqueductal Gray. Mol Neurobiol, 2016; 53(3):2036-53.
lLuJS, Yue F, Liu X, Chen T(*), Zhuo M*. Characterization of the anteriorcingulate cortex in adult tree shrew. Mol Pain. 2016Jan-Dec;12:1744806916684515.
lKoga,Kohei ,Descalzi,Giannina,Chen,Tao, Ko, Hyoung-Gon,Lu,Jinshan,Li,Shermaine,Son, Junehee,Kim,TaeHyun,Kwak,Chuljung,Huganir,Richard L,Zhao, Ming-Gao,Kaang,Bong-Kiun,Collingridge, Graham L,Zhuo,Min(*),Coexistenceof two forms of LTP in ACC provides a synaptic mechanism for the interactionsbetween anxiety and chronic pain. Neuron,2015,85(2):377-389.
lKoga,Kohei,Liu,Ming-Gang,Qiu, Shuang,Song,Qian,O'Den,Gerile,Chen,Tao,Zhuo,Min(*). Impaired presynaptic long-term potentiation in the anterior cingulatecortex of Fmr1 knock-out mice. Journal of Neuroscience,2015,35(5):2033-2043.
lChen,Tao(#), Lu, Jing-Shan,Song, Qian,Liu,Ming-Gang,Koga, Kohei,Descalzi,Giannina,Li,Yun-Qing,Zhuo,Min. Pharmacological rescue of cortical synaptic and network potentiation in amouse model for fragile X syndrome. Neuropsychopharmacology,2014,39(8):1955-1967.
lQiu,Shuang, Chen, Tao, Koga, Kohei,Guo, Yan-yan,Xu,Hui,Song,Qian,Wang,Jie-jie,Descalzi,Giannina,Kaang,Bong-Kiun,Luo, Jian-hong,Zhuo,Min,Zhao,Ming-gao,Anincrease in synaptic NMDA receptors in the insular cortex contributes toneuropathic pain. Sci Signal,2013,6(275):ra34-ra34.
lChen,Tao(#), O'Den, Gerile,Song, Qian,Koga,Kohei,Zhang,Ming-Ming,Zhuo, Min(*). Adenylyl cyclase subtype 1is essential for late-phase long termpotentiation and spatial propagation of synaptic responses in the anteriorcingulate cortex of adult mice. Molecular Pain,2014,10:65-65.
lChen,Tao(#), Wang, Wen,Dong,Yu-Lin,Zhang,Ming-Ming,Wang, Jian,Koga,Kohei,Liao,Yong-Hui,Li,Jin-Lian,Budisantoso,Timotheus,Shigemoto, Ryuichi,Itakura,Makoto,Huganir,Richard L,Li, Yun-Qing,Zhuo,Min. Postsynaptic insertion of AMPA receptor onto corticalpyramidal neurons in the anterior cingulate cortex after peripheral nerveinjury. Molecular Brain,2014, 7:76-76.
lChen,Tao(#), Koga, Kohei, Descalzi,Giannina,Qiu,Shuang,Wang,Jian,Zhang,Le-Shi,Zhang,Zhi-Jian,He,Xiao-Bin,Qin,Xin,Xu,Fu-Qiang,Hu,Ji,Wei,Feng,Huganir,Richard L,Li, Yun-Qing(*),Zhuo,Min. Postsynaptic potentiation of corticospinal projecting neurons in theanterior cingulate cortex after nerve injury.,MolecularPain,2014,10:33-33.
lChen,Lei,Zhu,Ling,Wang,Kun,Wang,Wei,Mei,Xiao-Peng,Liu, Tao,Zhang,Fu-Xing,Wang,Wen,Chen,Tao(*),Li, Yun-Qing. Antinociceptive effect ofprostatic acid phosphatase in a rat model of cancer-induced bone pain.,PainPhysician,2013,16(6):533-546
lChen,Tao(#), Wang, Xiao-Lin,Qu,Juan,Wang,Wei,Zhang,Ting,Yanagawa,Yuchio,Wu,Sheng-Xi,Li,Yun-Qing,Neurokinin-1 receptor-expressingneurons that contain serotonin and gamma-aminobutyric acid in the ratrostroventromedial medulla are involved in pain processing. Journal of Pain,2013,14(8):778-792
lLi,Xiang-Yao(#), Ko, Hyoung-Gon(#),Chen, Tao(#), Descalzi,Giannina,Koga,Kohei,Wang,Hansen,Kim,Susan S,Shang,Yuze,Kwak,Chuljung,Park,Soo-Won,Shim,Jaehoon,Lee,Kyungmin,Collingridge,Graham L,Kaang,Bong-Kiun,Zhuo, Min. Alleviating neuropathic painhypersensitivity by inhibiting PKMzeta in the anterior cingulate cortex. Science,2010,330(6009):1400-1404.
lChenT(#),Hui R, Wang XL, Zhang T, Dong YX,Li YQ. Origins of endomorphin-immunoreactive fibers and terminals in differentcolumns of the periaqueductal gray in the rat. J Comp Neurol. 2008 Jul1;509(1):72-87.